Hoodia gordonii (Masson)

@article{bruyns2014apocynaceae,

title = {The Apocynaceae of Namibia},

author = {Peter V Bruyns},

year  = {2014},

date = {2014-01-01},

publisher = {South African National Biodiversity Institute},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{JAIN201351,

title = {Metabolic effect of short term administration of Hoodia gordonii, an herbal appetite suppressant},

author = {S Jain and S N Singh},

url = {http://www.sciencedirect.com/science/article/pii/S0254629913000288},

doi = {https://doi.org/10.1016/j.sajb.2013.02.002},

issn = {0254-6299},

year  = {2013},

date = {2013-01-01},

journal = {South African Journal of Botany},

volume = {86},

pages = {51 - 55},

abstract = {Hoodia gordonii (family: Apocynaceae) is used traditionally by the Khoi-San tribes to control hunger. It has become extremely popular and has triggered commercial interest due to its appetite suppressant property. The present study was undertaken to investigate the appetite regulatory mechanism and associated metabolic changes induced by the herb. Effect of organic solvent extract of H. gordonii on food intake and body weight of male Sprague Dawley rats was monitored at three different doses 50, 100 and 150mg/kg body weight, given orally for five days. Subsequently, the dose of 100mg/kg body weight was selected for further studies on the regulatory hormones and biochemical variables. Dose-dependent reduction in food intake (12\textendash26%) was observed at a dose of 100 and 150mg/kg body weight (p\<0.05). Appetite suppression persisted for 6h and food intake was restored within 24h after stopping of the treatment. There was an increase in liver glycogen stores, activity of mitochondrial CPT-1 and thyroid hormones in treated animals. The circulating levels of NPY and IGF-1 were decreased with marginal increase in leptin and CCK, in case of treated rats. There was no change in blood glucose and insulin levels were not affected significantly. The hormonal and metabolic changes due to treatment with the H. gordonii extract may be responsible for its anorectic activity.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{VANHEERDEN2008434,

title = {Hoodia gordonii: A natural appetite suppressant},

author = {F R van Heerden},

url = {http://www.sciencedirect.com/science/article/pii/S0378874108004637},

doi = {https://doi.org/10.1016/j.jep.2008.08.023},

issn = {0378-8741},

year  = {2008},

date = {2008-01-01},

journal = {Journal of Ethnopharmacology},

volume = {119},

number = {3},

pages = {434 - 437},

abstract = {Aims of the study 

Several species of the stapeliads, a group of stem succulents belonging to the family Apocynaceae are reported on in the ethnopharmacology literature and many of the references relate to their use as food plants. The most important of these plants is Hoodia gordonii, which during the past decade has risen from an almost forgotten spiny, desert plant to an important commercial appetite-suppressant herbal. The aim of this review is to summarize the botany, ethnopharmacology and phytochemistry of Hoodia gordonii. 

Materials and methods 

Journal articles and books were used to collect information on Hoodia gordonii and related species. 

Results 

Many books and articles documented the use of stapeliad species as food plants and earlier references refer to the use Hoodia species as a thirst quencher. However, prior to the publication of the patent application, only a single reference referring to the use of Hoodia pilifera as appetite suppressant was found. The structures of several steroid glycosides isolated from Hoodia gordonii are summarized. 

Conclusions 

Hoodia gordonii illustrates how a combination of ethnobotany and scientific research can lead to a commercial product which can greatly benefit the indigenous people.},

note = {Ethnobotany in South Africa},

keywords = {},

pubstate = {published},

tppubtype = {article}

}